...biogenic immune theory [...] associates clinical depression with a neurotransmitter imbalance. ... But primary care doctors [overextended the theory which is reasonable for] clinical depression [to] everyday unhappiness... These are all leaps of faith. This is not real science.
If I hadn't worked at the FDA, I wouldn't have known that these negative trials [of antidepressants] existed. Later, when I came to academia, I saw a naiveté among my colleagues and medical professionals, this belief that if something is published in a journal, it must be so. I felt it was wrong that medical professionals, on the front lines treating patients, should be getting a sanitized view of drug efficacy—they need to know the whole story.